Vacation rentals in Seneca, SC

200 available vacation rental offers

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Best Vacation rentals and Airbnb offers in Seneca, SC

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy - Seneca, SC

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Cabin, Seneca

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy is a cabin in Seneca, with pet-friendly space, parking, and kitchen access. This stay gives travelers a comfortable base…

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About Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy is a cabin in Seneca, with pet-friendly space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: pet friendly, pets friendly, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,212.

From$117/night
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Beautiful home near Clemson - Seneca, SC

Beautiful home near Clemson

Holiday Home, Seneca

Beautiful home near Clemson is a holiday home in Seneca, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and…

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About Beautiful home near Clemson

Beautiful home near Clemson is a holiday home in Seneca, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $873.

From$125/night
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Historic Seneca Bungalow - Seneca, SC

Historic Seneca Bungalow

Holiday Home, Seneca

Historic Seneca Bungalow is a holiday home in Seneca, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and…

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About Historic Seneca Bungalow

Historic Seneca Bungalow is a holiday home in Seneca, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, kitchen, with kitchen, kids friendly, and kids friendly videos or books.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $959.

From$137/night
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Hanover Haven 3 BR/2 Bath - Seneca, SC

Hanover Haven 3 BR/2 Bath

Holiday Home, Seneca

Hanover Haven 3 BR/2 Bath is a holiday home in Seneca, with kitchen access and room for a group. This stay gives travelers a comfortable base for exploring the area, relaxing between…

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About Hanover Haven 3 BR/2 Bath

Hanover Haven 3 BR/2 Bath is a holiday home in Seneca, with kitchen access and room for a group. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and kids friendly.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $977.

From$140/night
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Browse Vacation Rentals with a Pool in Seneca, SC

Add a pool to the search when you want an easy place to cool off between outings.

The Hilltop Hideaway at Lake Hartwell - Seneca, SC

The Hilltop Hideaway at Lake Hartwell

Holiday Home, Seneca

The Hilltop Hideaway at Lake Hartwell is a holiday home in Seneca, with pool access and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between…

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About The Hilltop Hideaway at Lake Hartwell

The Hilltop Hideaway at Lake Hartwell is a holiday home in Seneca, with pool access and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: pool, free wifi, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,145.

From$164/night
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Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms - Seneca, SC

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

Condo, Seneca

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms is a condo in Seneca, with pool access and kitchen access. This stay gives travelers a comfortable base for…

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About Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms is a condo in Seneca, with pool access and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: pool, hot tub, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,180.

From$169/night
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Walk to Lake Keowee: Idyllic Six Mile Cabin! - Seneca, SC

Walk to Lake Keowee: Idyllic Six Mile Cabin!

Cabin, Seneca

Walk to Lake Keowee: Idyllic Six Mile Cabin! is a cabin in Seneca, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area,…

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About Walk to Lake Keowee: Idyllic Six Mile Cabin!

Walk to Lake Keowee: Idyllic Six Mile Cabin! is a cabin in Seneca, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pool, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,193.

From$170/night
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Walk to Clemson Univ & Downtown, Quiet & Safe Community, Pool, Free Parking - Seneca, SC

Walk to Clemson Univ & Downtown, Quiet & Safe Community, Pool, Free Parking

Condo, Seneca

Walk to Clemson Univ & Downtown, Quiet & Safe Community, Pool, Free Parking is a condo in Seneca, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base…

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About Walk to Clemson Univ & Downtown, Quiet & Safe Community, Pool, Free Parking

Walk to Clemson Univ & Downtown, Quiet & Safe Community, Pool, Free Parking is a condo in Seneca, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: pool, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,419.

From$203/night
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Best Seneca, SC vacation rentals with parking

Find vacation rentals that make arriving by car easier.

Seneca Escape w/ Screened Patio: Near Lakes! - Seneca, SC

Seneca Escape w/ Screened Patio: Near Lakes!

Apartment, Seneca

Seneca Escape w/ Screened Patio: Near Lakes! is a apartment in Seneca, with outdoor space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area,…

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About Seneca Escape w/ Screened Patio: Near Lakes!

Seneca Escape w/ Screened Patio: Near Lakes! is a apartment in Seneca, with outdoor space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,958.

From$215/night
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Charming Seneca Home - 3 Mi to Memorial Stadium! - Seneca, SC

Charming Seneca Home - 3 Mi to Memorial Stadium!

Holiday Home, Seneca

Charming Seneca Home - 3 Mi to Memorial Stadium! is a holiday home in Seneca, with parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings,…

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About Charming Seneca Home - 3 Mi to Memorial Stadium!

Charming Seneca Home - 3 Mi to Memorial Stadium! is a holiday home in Seneca, with parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, parking, paid parking, and heating.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,285.

From$232/night
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Spring Retreat~Early Season Discounts~Experience the Best of the Upstate - Seneca, SC

Spring Retreat~Early Season Discounts~Experience the Best of the Upstate

Holiday Home, Seneca

Spring Retreat~Early Season Discounts~Experience the Best of the Upstate is a holiday home in Seneca, with parking, kitchen access, and a quieter setting. This stay gives travelers a…

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About Spring Retreat~Early Season Discounts~Experience the Best of the Upstate

Spring Retreat~Early Season Discounts~Experience the Best of the Upstate is a holiday home in Seneca, with parking, kitchen access, and a quieter setting. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,694.

From$242/night
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Seneca Escape w/ Screened Patio: Near Lakes! - Seneca, SC

Seneca Escape w/ Screened Patio: Near Lakes!

Holiday Home, Seneca

Seneca Escape w/ Screened Patio: Near Lakes! is a holiday home in Seneca, with outdoor space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the…

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About Seneca Escape w/ Screened Patio: Near Lakes!

Seneca Escape w/ Screened Patio: Near Lakes! is a holiday home in Seneca, with outdoor space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,724.

From$246/night
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Best Pet-Friendly Vacation Rentals in Seneca, SC

Bring your pet along with stays that welcome four-legged travelers.

NO CLEANING FEE Century farmhouse on Lake Keowee near Clemson - Seneca, SC

NO CLEANING FEE Century farmhouse on Lake Keowee near Clemson

Holiday Home, Seneca

NO CLEANING FEE Century farmhouse on Lake Keowee near Clemson is a holiday home in Seneca, with pet-friendly space, parking, and kitchen access. This stay gives travelers a comfortable base…

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About NO CLEANING FEE Century farmhouse on Lake Keowee near Clemson

NO CLEANING FEE Century farmhouse on Lake Keowee near Clemson is a holiday home in Seneca, with pet-friendly space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pet friendly, pets friendly, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,215.

From$174/night
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Fabulous Tiny House with AC in charming Seneca - Seneca, SC

Fabulous Tiny House with AC in charming Seneca

Cabin, Seneca

Fabulous Tiny House with AC in charming Seneca is a cabin in Seneca, with pet-friendly space and parking. This stay gives travelers a comfortable base for exploring the area, relaxing…

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About Fabulous Tiny House with AC in charming Seneca

Fabulous Tiny House with AC in charming Seneca is a cabin in Seneca, with pet-friendly space and parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pet friendly, pets friendly, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,261.

From$180/night
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Cozy Seneca Getaway • Pet Friendly • Sleeps 7! - Seneca, SC

Cozy Seneca Getaway • Pet Friendly • Sleeps 7!

Holiday Home, Seneca

Cozy Seneca Getaway · Pet Friendly · Sleeps 7! is a holiday home in Seneca, with pet-friendly space, kitchen access, and room for a group. This stay gives travelers a comfortable base for…

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About Cozy Seneca Getaway • Pet Friendly • Sleeps 7!

Cozy Seneca Getaway · Pet Friendly · Sleeps 7! is a holiday home in Seneca, with pet-friendly space, kitchen access, and room for a group. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pet friendly, pets friendly, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,444.

From$206/night
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3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson - Seneca, SC

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

Holiday Home, Seneca

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson is a holiday home in Seneca, with pet-friendly space, parking, and kitchen access. This stay gives travelers…

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About 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson is a holiday home in Seneca, with pet-friendly space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pet friendly, pets friendly, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,821.

From$260/night
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Best Seneca, SC vacation rentals with a kitchen

Compare stays with kitchen access for longer trips and easier meals.

Royal Summit Bungalow - Seneca, SC

Royal Summit Bungalow

Holiday Home, Seneca

Royal Summit Bungalow is a holiday home in Seneca, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and…

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About Royal Summit Bungalow

Royal Summit Bungalow is a holiday home in Seneca, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,764.

From$252/night
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Charming Seneca Home - 3 Mi to Memorial Stadium! - Seneca, SC

Charming Seneca Home - 3 Mi to Memorial Stadium!

Apartment, Seneca

Charming Seneca Home - 3 Mi to Memorial Stadium! is a apartment in Seneca, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing…

Read more

About Charming Seneca Home - 3 Mi to Memorial Stadium!

Charming Seneca Home - 3 Mi to Memorial Stadium! is a apartment in Seneca, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,372.

From$269/night
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6 Mi to South Cove Boat Ramp! Lake Keowee Escape - Seneca, SC

6 Mi to South Cove Boat Ramp! Lake Keowee Escape

Cottage, Seneca

6 Mi to South Cove Boat Ramp! Lake Keowee Escape is a cottage in Seneca, with kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings,…

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About 6 Mi to South Cove Boat Ramp! Lake Keowee Escape

6 Mi to South Cove Boat Ramp! Lake Keowee Escape is a cottage in Seneca, with kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, hot tub, free wifi, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,398.

From$281/night
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The Nest Above- Hummingbird - Seneca, SC

The Nest Above- Hummingbird

Apartment, Seneca

The Nest Above- Hummingbird is a apartment in Seneca, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and…

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About The Nest Above- Hummingbird

The Nest Above- Hummingbird is a apartment in Seneca, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,622.

From$375/night
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Our Favorite Family-Friendly Vacation Rentals in Seneca, SC

Plan a trip with stays that give families more room to spread out.

Private setting close to Clemson University - Seneca, SC

Private setting close to Clemson University

Holiday Home, Seneca

Private setting close to Clemson University is a holiday home in Seneca, with kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings,…

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About Private setting close to Clemson University

Private setting close to Clemson University is a holiday home in Seneca, with kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and kids friendly.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,046.

From$149/night
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Wooded Cottage - 3 Mi to Clemson University - Seneca, SC

Wooded Cottage - 3 Mi to Clemson University

Holiday Home, Seneca

Wooded Cottage - 3 Mi to Clemson University is a holiday home in Seneca, with pet-friendly space and parking. This stay gives travelers a comfortable base for exploring the area, relaxing…

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About Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University is a holiday home in Seneca, with pet-friendly space and parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free wifi, pet friendly, pets friendly, parking, and paid parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,522.

From$155/night
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Cozy cottage quiet and secluded but close to everything. - Seneca, SC

Cozy cottage quiet and secluded but close to everything.

Cottage, Seneca

Cozy cottage quiet and secluded but close to everything. is a cottage in Seneca, with parking, kitchen access, and a quieter setting. This stay gives travelers a comfortable base for…

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About Cozy cottage quiet and secluded but close to everything.

Cozy cottage quiet and secluded but close to everything. is a cottage in Seneca, with parking, kitchen access, and a quieter setting. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,197.

From$171/night
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Clemson Cottage -close to University and lakes - Seneca, SC

Clemson Cottage -close to University and lakes

Apartment, Seneca

Clemson Cottage -close to University and lakes is a apartment in Seneca, with pet-friendly space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the…

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About Clemson Cottage -close to University and lakes

Clemson Cottage -close to University and lakes is a apartment in Seneca, with pet-friendly space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pet friendly, pets friendly, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,220.

From$174/night
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