Vacation rentals in Santee, SC

34 available vacation rental offers

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Best vacation rentals and Airbnb offers in Santee, SC

Pet friendly country cottage with large fenced-in yard & horses on property - Santee, SC

Pet friendly country cottage with large fenced-in yard & horses on property

Cottage, Santee

Pet friendly country cottage with large fenced-in yard & horses on property is a cottage in Santee, with pet-friendly space and kitchen access. This stay gives travelers a comfortable base…

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About Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property is a cottage in Santee, with pet-friendly space and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, pet friendly, pets friendly, and kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $966.

From$138/night
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Modern apartment overlooking historic downtown Elloree, SC. - Santee, SC

Modern apartment overlooking historic downtown Elloree, SC.

Apartment, Santee

Modern apartment overlooking historic downtown Elloree, SC. is a apartment in Santee, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area,…

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About Modern apartment overlooking historic downtown Elloree, SC.

Modern apartment overlooking historic downtown Elloree, SC. is a apartment in Santee, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,005.

From$144/night
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Sunsets on Lake Marion: 2BD Lakefront Luxury Bliss - Santee, SC

Sunsets on Lake Marion: 2BD Lakefront Luxury Bliss

Condo, Santee

Sunsets on Lake Marion: 2BD Lakefront Luxury Bliss is a condo in Santee, with pet-friendly space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the…

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About Sunsets on Lake Marion: 2BD Lakefront Luxury Bliss

Sunsets on Lake Marion: 2BD Lakefront Luxury Bliss is a condo in Santee, with pet-friendly space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pet friendly, pets friendly, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,207.

From$172/night
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Taw Caw Creek Rental - perfect for fishermen - NO PETS - Santee, SC

Taw Caw Creek Rental - perfect for fishermen - NO PETS

Holiday Home, Santee

Taw Caw Creek Rental - perfect for fishermen - NO PETS is a holiday home in Santee, with pet-friendly space and parking. This stay gives travelers a comfortable base for exploring the area,…

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About Taw Caw Creek Rental - perfect for fishermen - NO PETS

Taw Caw Creek Rental - perfect for fishermen - NO PETS is a holiday home in Santee, with pet-friendly space and parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, parking, free parking, washer, and dryer.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,218.

From$174/night
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Vacation rentals with parking in Santee, SC

Find vacation rentals that make arriving by car easier.

Lake Home walking distance to Marina and 2 more boat landings within a Mile! - Santee, SC

Lake Home walking distance to Marina and 2 more boat landings within a Mile!

Holiday Home, Santee

Lake Home walking distance to Marina and 2 more boat landings within a Mile! is a holiday home in Santee, with parking and kitchen access. This stay gives travelers a comfortable base for…

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About Lake Home walking distance to Marina and 2 more boat landings within a Mile!

Lake Home walking distance to Marina and 2 more boat landings within a Mile! is a holiday home in Santee, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,218.

From$174/night
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Dukes Street Retreat 5min from I-95! - Santee, SC

Dukes Street Retreat 5min from I-95!

Holiday Home, Santee

Dukes Street Retreat 5min from I-95! is a holiday home in Santee, with parking, kitchen access, and a quieter setting. This stay gives travelers a comfortable base for exploring the area,…

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About Dukes Street Retreat 5min from I-95!

Dukes Street Retreat 5min from I-95! is a holiday home in Santee, with parking, kitchen access, and a quieter setting. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,463.

From$209/night
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The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot. - Santee, SC

The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.

Holiday Home, Santee

The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot. is a holiday home in Santee, with parking, kitchen access, and a quieter setting. This stay gives travelers a…

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About The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.

The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot. is a holiday home in Santee, with parking, kitchen access, and a quieter setting. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,620.

From$231/night
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3-bedroom house in fabulous Summerton next to lake - Santee, SC

3-bedroom house in fabulous Summerton next to lake

Holiday Home, Santee

3-bedroom house in fabulous Summerton next to lake is a holiday home in Santee, with parking, kitchen access, and room for a group. This stay gives travelers a comfortable base for…

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About 3-bedroom house in fabulous Summerton next to lake

3-bedroom house in fabulous Summerton next to lake is a holiday home in Santee, with parking, kitchen access, and room for a group. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,842.

From$263/night
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Pet-friendly vacation rentals in Santee, SC

Bring your pet along with stays that welcome four-legged travelers.

Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!! - Santee, SC

Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!

Holiday Home, Santee

Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!! is a holiday home in Santee, with pet-friendly space and kitchen access. This stay gives travelers a comfortable…

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About Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!

Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!! is a holiday home in Santee, with pet-friendly space and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, pet friendly, pets friendly, and kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,305.

From$186/night
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Annie's Place- A great Day at Lake Marion, SC - Santee, SC

Annie's Place- A great Day at Lake Marion, SC

Holiday Home, Santee

Annie's Place- A great Day at Lake Marion, SC is a holiday home in Santee, with pet-friendly space and kitchen access. This stay gives travelers a comfortable base for exploring the area,…

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About Annie's Place- A great Day at Lake Marion, SC

Annie's Place- A great Day at Lake Marion, SC is a holiday home in Santee, with pet-friendly space and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, pet friendly, pets friendly, and kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,518.

From$217/night
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4BD | 3BTH | Pool | HotTub | Games |5Miles to I-95 - Santee, SC

4BD | 3BTH | Pool | HotTub | Games |5Miles to I-95

Holiday Home, Santee

4BD · 3BTH · Pool · HotTub · Games · 5Miles to I-95 is a holiday home in Santee, with pet-friendly space and pool access. This stay gives travelers a comfortable base for exploring the…

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About 4BD | 3BTH | Pool | HotTub | Games |5Miles to I-95

4BD · 3BTH · Pool · HotTub · Games · 5Miles to I-95 is a holiday home in Santee, with pet-friendly space and pool access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: pool, hot tub, pet friendly, and pets friendly.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,934.

From$276/night
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Viridian Retreat - Santee, SC

Viridian Retreat

Holiday Home, Santee

Viridian Retreat is a holiday home in Santee, with pet-friendly space, kitchen access, and a quieter setting. This stay gives travelers a comfortable base for exploring the area, relaxing…

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About Viridian Retreat

Viridian Retreat is a holiday home in Santee, with pet-friendly space, kitchen access, and a quieter setting. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, pet friendly, pets friendly, and kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,200.

From$314/night
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Vacation rentals with a kitchen in Santee, SC

Compare stays with kitchen access for longer trips and easier meals.

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8 - Santee, SC

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

Cabin, Santee

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8 is a cabin in Santee, with parking, kitchen access, and room for a group. This stay gives travelers a comfortable base for exploring…

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About Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8 is a cabin in Santee, with parking, kitchen access, and room for a group. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,813.

From$259/night
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Well-Equipped Lakefront Home on a Large Lot with Dock Access and Sunset Views - Santee, SC

Well-Equipped Lakefront Home on a Large Lot with Dock Access and Sunset Views

Holiday Home, Santee

Well-Equipped Lakefront Home on a Large Lot with Dock Access and Sunset Views is a holiday home in Santee, with parking and kitchen access. This stay gives travelers a comfortable base for…

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About Well-Equipped Lakefront Home on a Large Lot with Dock Access and Sunset Views

Well-Equipped Lakefront Home on a Large Lot with Dock Access and Sunset Views is a holiday home in Santee, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,074.

From$296/night
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Taw Caw Creek Waterfront, Dock, Sandy Beach, Minutes To Big Water! NO PETS - Santee, SC

Taw Caw Creek Waterfront, Dock, Sandy Beach, Minutes To Big Water! NO PETS

Holiday Home, Santee

Taw Caw Creek Waterfront, Dock, Sandy Beach, Minutes To Big Water! NO PETS is a holiday home in Santee, with pet-friendly space, easy beach access, and parking. This stay gives travelers a…

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About Taw Caw Creek Waterfront, Dock, Sandy Beach, Minutes To Big Water! NO PETS

Taw Caw Creek Waterfront, Dock, Sandy Beach, Minutes To Big Water! NO PETS is a holiday home in Santee, with pet-friendly space, easy beach access, and parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,175.

From$311/night
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Spacious Family Home on Lake Marion w/ Boat Ramp! - Santee, SC

Spacious Family Home on Lake Marion w/ Boat Ramp!

Cottage, Santee

Spacious Family Home on Lake Marion w/ Boat Ramp! is a cottage in Santee, with parking, kitchen access, and room for a group. This stay gives travelers a comfortable base for exploring the…

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About Spacious Family Home on Lake Marion w/ Boat Ramp!

Spacious Family Home on Lake Marion w/ Boat Ramp! is a cottage in Santee, with parking, kitchen access, and room for a group. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,968.

From$350/night
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Family-friendly vacation rentals in Santee, SC

Plan a trip with stays that give families more room to spread out.

Tranquility Cottage Getaways W/Heated Pool and Fishing - Santee, SC

Tranquility Cottage Getaways W/Heated Pool and Fishing

Cottage, Santee

Tranquility Cottage Getaways W/Heated Pool and Fishing is a cottage in Santee, with pool access and kitchen access. This stay gives travelers a comfortable base for exploring the area,…

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About Tranquility Cottage Getaways W/Heated Pool and Fishing

Tranquility Cottage Getaways W/Heated Pool and Fishing is a cottage in Santee, with pool access and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: pool, free wifi, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,751.

From$250/night
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The Bunkhouse at St Julien - Vintage Waterfront Lake House - Santee, SC

The Bunkhouse at St Julien - Vintage Waterfront Lake House

Holiday Home, Santee

The Bunkhouse at St Julien - Vintage Waterfront Lake House is a holiday home in Santee, with pet-friendly space, easy beach access, and kitchen access. This stay gives travelers a…

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About The Bunkhouse at St Julien - Vintage Waterfront Lake House

The Bunkhouse at St Julien - Vintage Waterfront Lake House is a holiday home in Santee, with pet-friendly space, easy beach access, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pet friendly, pets friendly, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,093.

From$299/night
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Spacious Family Home on Lake Marion w/ Boat Ramp! - Santee, SC

Spacious Family Home on Lake Marion w/ Boat Ramp!

Holiday Home, Santee

Spacious Family Home on Lake Marion w/ Boat Ramp! is a holiday home in Santee, with parking and room for a group. This stay gives travelers a comfortable base for exploring the area,…

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About Spacious Family Home on Lake Marion w/ Boat Ramp!

Spacious Family Home on Lake Marion w/ Boat Ramp! is a holiday home in Santee, with parking and room for a group. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, parking, paid parking, and heating.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,861.

From$310/night
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Idyllic Waterfront Escape w/ Private Boat Dock! - Santee, SC

Idyllic Waterfront Escape w/ Private Boat Dock!

Cottage, Santee

Idyllic Waterfront Escape w/ Private Boat Dock! is a cottage in Santee, with easy beach access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the…

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About Idyllic Waterfront Escape w/ Private Boat Dock!

Idyllic Waterfront Escape w/ Private Boat Dock! is a cottage in Santee, with easy beach access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,959.

From$348/night
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