Vacation rentals in North Santee River, SC

45 available vacation rental offers

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Best vacation rentals and Airbnb offers in North Santee River, SC

Georgetown cottage cozy, updated 2 bedroom 3 blocks from historic downtown - North Santee River, SC

Georgetown cottage cozy, updated 2 bedroom 3 blocks from historic downtown

Cottage, North Santee River

Georgetown cottage cozy, updated 2 bedroom 3 blocks from historic downtown is a cottage in North Santee River, with room for a group. This stay gives travelers a comfortable base for…

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About Georgetown cottage cozy, updated 2 bedroom 3 blocks from historic downtown

Georgetown cottage cozy, updated 2 bedroom 3 blocks from historic downtown is a cottage in North Santee River, with room for a group. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, washer, dryer, ac, and air conditioning.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $686.

From$98/night
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Baxter's Brewhouse Inn - North Santee River, SC

Baxter's Brewhouse Inn

B & B, North Santee River

Baxter's Brewhouse Inn is a b & b in North Santee River, with parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with…

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About Baxter's Brewhouse Inn

Baxter's Brewhouse Inn is a b & b in North Santee River, with parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free breakfast, free wifi, parking, free parking, and ac.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $972.

From$125/night
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427 Broad Street - Downtown Georgetown - North Santee River, SC

427 Broad Street - Downtown Georgetown

Apartment, North Santee River

427 Broad Street - Downtown Georgetown is a apartment in North Santee River, with kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between…

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About 427 Broad Street - Downtown Georgetown

427 Broad Street - Downtown Georgetown is a apartment in North Santee River, with kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, kitchen, with kitchen, and kids friendly.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $945.

From$135/night
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'Magnolia House' 1 Mi to Historic Georgetown - North Santee River, SC

'Magnolia House' 1 Mi to Historic Georgetown

Holiday Home, North Santee River

'Magnolia House' 1 Mi to Historic Georgetown is a holiday home in North Santee River, with parking. This stay gives travelers a comfortable base for exploring the area, relaxing between…

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About 'Magnolia House' 1 Mi to Historic Georgetown

'Magnolia House' 1 Mi to Historic Georgetown is a holiday home in North Santee River, with parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, hot tub, free wifi, parking, and paid parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,490.

From$144/night
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Vacation rentals with a pool in North Santee River, SC

Add a pool to the search when you want an easy place to cool off between outings.

Poolside Villas @ Winyah Bay Club! - North Santee River, SC

Poolside Villas @ Winyah Bay Club!

Holiday Home, North Santee River

Poolside Villas @ Winyah Bay Club! is a holiday home in North Santee River, with pool access, easy beach access, and parking. This stay gives travelers a comfortable base for exploring the…

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About Poolside Villas @ Winyah Bay Club!

Poolside Villas @ Winyah Bay Club! is a holiday home in North Santee River, with pool access, easy beach access, and parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pool, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,358.

From$337/night
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Winyah Bay Club - North Santee River, SC

Winyah Bay Club

Condo, North Santee River

Winyah Bay Club is a condo in North Santee River, with pool access, easy beach access, and parking. This stay gives travelers a comfortable base for exploring the area, relaxing between…

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About Winyah Bay Club

Winyah Bay Club is a condo in North Santee River, with pool access, easy beach access, and parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pool, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,857.

From$338/night
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Poolside Villas @ Winyah Bay Club! - North Santee River, SC

Poolside Villas @ Winyah Bay Club!

Holiday Home, North Santee River

Poolside Villas @ Winyah Bay Club! is a holiday home in North Santee River, with pool access, easy beach access, and parking. This stay gives travelers a comfortable base for exploring the…

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About Poolside Villas @ Winyah Bay Club!

Poolside Villas @ Winyah Bay Club! is a holiday home in North Santee River, with pool access, easy beach access, and parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pool, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,390.

From$341/night
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Creekside Villa w. Pool + Boat Slip - North Santee River, SC

Creekside Villa w. Pool + Boat Slip

Holiday Home, North Santee River

Creekside Villa w. Pool + Boat Slip is a holiday home in North Santee River, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the…

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About Creekside Villa w. Pool + Boat Slip

Creekside Villa w. Pool + Boat Slip is a holiday home in North Santee River, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pool, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,579.

From$368/night
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Vacation rentals with parking in North Santee River, SC

Find vacation rentals that make arriving by car easier.

Charming Georgetown bungalow within walking distance to downtown & boat access - North Santee River, SC

Charming Georgetown bungalow within walking distance to downtown & boat access

Holiday Home, North Santee River

Charming Georgetown bungalow within walking distance to downtown & boat access is a holiday home in North Santee River, with parking and kitchen access. This stay gives travelers a…

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About Charming Georgetown bungalow within walking distance to downtown & boat access

Charming Georgetown bungalow within walking distance to downtown & boat access is a holiday home in North Santee River, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,618.

From$231/night
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Cypress Chaos beautiful home with incredible marsh views in Willowbank - North Santee River, SC

Cypress Chaos beautiful home with incredible marsh views in Willowbank

Holiday Home, North Santee River

Cypress Chaos beautiful home with incredible marsh views in Willowbank is a holiday home in North Santee River, with parking and kitchen access. This stay gives travelers a comfortable base…

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About Cypress Chaos beautiful home with incredible marsh views in Willowbank

Cypress Chaos beautiful home with incredible marsh views in Willowbank is a holiday home in North Santee River, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free wifi, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,219.

From$317/night
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Spacious living in Historic Georgetown with shops, dining, museums steps away! - North Santee River, SC

Spacious living in Historic Georgetown with shops, dining, museums steps away!

Apartment, North Santee River

Spacious living in Historic Georgetown with shops, dining, museums steps away! is a apartment in North Santee River, with parking and kitchen access. This stay gives travelers a comfortable…

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About Spacious living in Historic Georgetown with shops, dining, museums steps away!

Spacious living in Historic Georgetown with shops, dining, museums steps away! is a apartment in North Santee River, with parking and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, hot tub, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,287.

From$327/night
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St. Germaine 3 Bedroom Updated historical home in Georgetown SC MAIN LEVEL - North Santee River, SC

St. Germaine 3 Bedroom Updated historical home in Georgetown SC MAIN LEVEL

Holiday Home, North Santee River

St. Germaine 3 Bedroom Updated historical home in Georgetown SC MAIN LEVEL is a holiday home in North Santee River, with parking, kitchen access, and room for a group. This stay gives…

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About St. Germaine 3 Bedroom Updated historical home in Georgetown SC MAIN LEVEL

St. Germaine 3 Bedroom Updated historical home in Georgetown SC MAIN LEVEL is a holiday home in North Santee River, with parking, kitchen access, and room for a group. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free wifi, kitchen, with kitchen, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,729.

From$390/night
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Pet-friendly vacation rentals in North Santee River, SC

Bring your pet along with stays that welcome four-legged travelers.

Cute Georgetown Villa < 1 Mi to Historic District - North Santee River, SC

Cute Georgetown Villa < 1 Mi to Historic District

Villa, North Santee River

Cute Georgetown Villa < 1 Mi to Historic District is a villa in North Santee River, with pet-friendly space, parking, and kitchen access. This stay gives travelers a comfortable base for…

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About Cute Georgetown Villa < 1 Mi to Historic District

Cute Georgetown Villa < 1 Mi to Historic District is a villa in North Santee River, with pet-friendly space, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pet friendly, pets friendly, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,562.

From$223/night
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Cute Georgetown Villa < 1 Mi to Historic District - North Santee River, SC

Cute Georgetown Villa < 1 Mi to Historic District

Villa, North Santee River

Cute Georgetown Villa < 1 Mi to Historic District is a villa in North Santee River, with pet-friendly space and kitchen access. This stay gives travelers a comfortable base for exploring…

Read more

About Cute Georgetown Villa < 1 Mi to Historic District

Cute Georgetown Villa < 1 Mi to Historic District is a villa in North Santee River, with pet-friendly space and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, pet friendly, pets friendly, and kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,897.

From$224/night
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3 Bdrm in Georgetown's Historic District - North Santee River, SC

3 Bdrm in Georgetown's Historic District

Holiday Home, North Santee River

3 Bdrm in Georgetown's Historic District is a holiday home in North Santee River, with pet-friendly space and parking. This stay gives travelers a comfortable base for exploring the area,…

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About 3 Bdrm in Georgetown's Historic District

3 Bdrm in Georgetown's Historic District is a holiday home in North Santee River, with pet-friendly space and parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, free wifi, pet friendly, pets friendly, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,700.

From$263/night
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The Red Door House in Historic Georgetown - North Santee River, SC

The Red Door House in Historic Georgetown

Holiday Home, North Santee River

The Red Door House in Historic Georgetown is a holiday home in North Santee River, with pet-friendly space, pool access, and kitchen access. This stay gives travelers a comfortable base for…

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About The Red Door House in Historic Georgetown

The Red Door House in Historic Georgetown is a holiday home in North Santee River, with pet-friendly space, pool access, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: pool, pet friendly, pets friendly, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,946.

From$278/night
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Vacation rentals with a kitchen in North Santee River, SC

Compare stays with kitchen access for longer trips and easier meals.

3 Bdrm in Georgetown's Historic District - North Santee River, SC

3 Bdrm in Georgetown's Historic District

Holiday Home, North Santee River

3 Bdrm in Georgetown's Historic District is a holiday home in North Santee River, with pet-friendly space and kitchen access. This stay gives travelers a comfortable base for exploring the…

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About 3 Bdrm in Georgetown's Historic District

3 Bdrm in Georgetown's Historic District is a holiday home in North Santee River, with pet-friendly space and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: hot tub, pet friendly, pets friendly, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,614.

From$373/night
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Apartment with Dockage-Georgetown waterfront - North Santee River, SC

Apartment with Dockage-Georgetown waterfront

Apartment, North Santee River

Apartment with Dockage-Georgetown waterfront is a apartment in North Santee River, with pet-friendly space, easy beach access, and parking. This stay gives travelers a comfortable base for…

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About Apartment with Dockage-Georgetown waterfront

Apartment with Dockage-Georgetown waterfront is a apartment in North Santee River, with pet-friendly space, easy beach access, and parking. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pet friendly, pets friendly, kitchen, and with kitchen.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,792.

From$399/night
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Marsh View Cottage with Pool + Boat Slip - North Santee River, SC

Marsh View Cottage with Pool + Boat Slip

Holiday Home, North Santee River

Marsh View Cottage with Pool + Boat Slip is a holiday home in North Santee River, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring…

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About Marsh View Cottage with Pool + Boat Slip

Marsh View Cottage with Pool + Boat Slip is a holiday home in North Santee River, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pool, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,861.

From$409/night
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Marsh View Cottage with Pool + Boat Slip - North Santee River, SC

Marsh View Cottage with Pool + Boat Slip

Holiday Home, North Santee River

Marsh View Cottage with Pool + Boat Slip is a holiday home in North Santee River, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring…

Read more

About Marsh View Cottage with Pool + Boat Slip

Marsh View Cottage with Pool + Boat Slip is a holiday home in North Santee River, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pool, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,861.

From$409/night
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Family-friendly vacation rentals in North Santee River, SC

Plan a trip with stays that give families more room to spread out.

Great 2-bedroom, 2-bath cottage in Georgetown 2-blocks, 7-minutes to boardwalk - North Santee River, SC

Great 2-bedroom, 2-bath cottage in Georgetown 2-blocks, 7-minutes to boardwalk

Cottage, North Santee River

Great 2-bedroom, 2-bath cottage in Georgetown 2-blocks, 7-minutes to boardwalk is a cottage in North Santee River, with pet-friendly space and room for a group. This stay gives travelers a…

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About Great 2-bedroom, 2-bath cottage in Georgetown 2-blocks, 7-minutes to boardwalk

Great 2-bedroom, 2-bath cottage in Georgetown 2-blocks, 7-minutes to boardwalk is a cottage in North Santee River, with pet-friendly space and room for a group. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pet friendly, pets friendly, washer, and dryer.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,708.

From$244/night
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Delightful 2-bedroom cottage in charming Georgetown - North Santee River, SC

Delightful 2-bedroom cottage in charming Georgetown

Cottage, North Santee River

Delightful 2-bedroom cottage in charming Georgetown is a cottage in North Santee River, with pet-friendly space, parking, and room for a group. This stay gives travelers a comfortable base…

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About Delightful 2-bedroom cottage in charming Georgetown

Delightful 2-bedroom cottage in charming Georgetown is a cottage in North Santee River, with pet-friendly space, parking, and room for a group. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pet friendly, pets friendly, parking, and free parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $1,985.

From$284/night
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Marsh View Cottage with Pool + Boat Slip - North Santee River, SC

Marsh View Cottage with Pool + Boat Slip

Holiday Home, North Santee River

Marsh View Cottage with Pool + Boat Slip is a holiday home in North Santee River, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring…

Read more

About Marsh View Cottage with Pool + Boat Slip

Marsh View Cottage with Pool + Boat Slip is a holiday home in North Santee River, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pool, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,823.

From$403/night
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Marsh View Cottage with Pool + Boat Slip - North Santee River, SC

Marsh View Cottage with Pool + Boat Slip

Holiday Home, North Santee River

Marsh View Cottage with Pool + Boat Slip is a holiday home in North Santee River, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring…

Read more

About Marsh View Cottage with Pool + Boat Slip

Marsh View Cottage with Pool + Boat Slip is a holiday home in North Santee River, with pool access, parking, and kitchen access. This stay gives travelers a comfortable base for exploring the area, relaxing between outings, and spending time with family or friends.

Useful features: free cancellation, pool, kitchen, with kitchen, and parking.

Sat, Aug 29 - Sat, Sep 5 · 7 nights · total from $2,823.

From$403/night
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